Hello @hausofpayne ESP32 allows to assign almost any functionality (SPI, I2C, etc.) to almost any GPIOs. Using the example GxEPD2_WS_ESP32_Driver.ino from the GxEPD2 library with the following GPIO setup worked for me. (Note: I used a Waveshare 2.9" ePaper for my test.) DI <--> 26 SCK <--> 18 CS <--> 21 DC <--> 22 BUSY <--> 32 RESET <--> 33 On line 118 of the example you set the GPIOs for CS, DC, RST and BUSY: GxEPD2_DISPLAY_CLASS<GxEPD2_DRIVER_CLASS, MAX_HEIGHT(GxEPD2_DRIVER_CLASS)> display(GxEPD2_DRIVER_CLASS(/*CS=*/ 21, /*DC=*/ 22, /*RST=*/ 33, /*BUSY=*/ 32)); On line 150 of the example you set the GPIOs for SPI: SPI.begin(18, 36, 26, 21); // map and init SPI pins SCK(18), MISO(36), MOSI(26), SS(21) Thanks Felix