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Using Cenforce 120 mg alongside other PDE5 inhibitors—such as Tadalafil, Vardenafil, or other Sildenafil-based medications—can lead to excessive vasodilation. This may cause a sudden drop in blood pressure, dizziness, fainting, or even cardiovascular complications, especially in men with heart conditions. Similarly, combining it with nitrate medications (commonly used for chest pain or heart problems) is strictly contraindicated, as this can result in life-threatening hypotension.