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Tadalista CT 20 mg works by relaxing the smooth muscles in the blood vessels of the penis, which allows more blood to flow into the area when a man is sexually aroused. The increased blood flow helps to achieve and sustain a firm erection.Tadalafil, the main ingredient in Tadalista, helps prevent the breakdown of cyclic GMP (a substance responsible for smooth muscle relaxation), thus facilitating improved blood flow to the penis.